| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 11B1, mitochondrial |
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| Ligand | BDBM50028169 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_192 |
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| IC50 | 660.0±n/a nM |
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| Citation |  Hays, SJ; Tobes, MC; Gildersleeve, DL; Wieland, DM; Beierwaltes, WH Structure-activity relationship study of the inhibition of adrenal cortical 11 beta-hydroxylase by new metyrapone analogues. J Med Chem27:15-9 (1984) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 11B1, mitochondrial |
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| Name: | Cytochrome P450 11B1, mitochondrial |
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| Synonyms: | C11B1_BOVIN | CYP11B1 | Cytochrome P450 11B1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57863.81 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_1345884 |
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| Residue: | 503 |
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| Sequence: | MALWAKARVRMAGPWLSLHEARLLGTRGAAAPKAVLPFEAMPRCPGNKWMRMLQIWKEQS
SENMHLDMHQTFQELGPIFRYDVGGRHMVFVMLPEDVERLQQADSHHPQRMILEPWLAYR
QARGHKCGVFLLNGPQWRLDRLRLNPDVLSLPALQKYTPLVDGVARDFSQTLKARVLQNA
RGSLTLDIAPSVFRYTIEASTLVLYGERLGLLTQQPNPDSLNFIHALEAMLKSTVQLMFV
PRRLSRWMSTNMWREHFEAWDYIFQYANRAIQRIYQELALGHPWHYSGIVAELLMRADMT
LDTIKANTIDLTAGSVDTTAFPLLMTLFELARNPEVQQAVRQESLVAEARISENPQRAIT
ELPLLRAALKETLRLYPVGITLEREVSSDLVLQNYHIPAGTLVKVLLYSLGRNPAVFARP
ESYHPQRWLDRQGSGSRFPHLAFGFGVRQCLGRRVAEVEMLLLLHHVLKNFLVETLEQED
IKMVYRFILMPSTLPLFTFRAIQ
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| BDBM50028169 |
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| n/a |
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| Name | BDBM50028169 |
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| Synonyms: | 3-(1,1-Dimethyl-2-phenyl-ethyl)-pyridine | CHEMBL440299 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H17N |
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| Mol. Mass. | 211.3022 |
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| SMILES | CC(C)(Cc1ccccc1)c1cccnc1 |
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| Structure | 
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