| Reaction Details |
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 | Report a problem with these data |
| Target | Catechol O-methyltransferase |
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| Ligand | BDBM50028548 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_47077 |
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| Ki | 3460000±n/a nM |
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| Citation |  Borchardt, RT; Bhatia, P Catechol O-methyltransferase. 12. Affinity labeling the active site with the oxidation products of 5,6-dihydroxyindole. J Med Chem25:263-71 (1982) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Catechol O-methyltransferase |
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| Name: | Catechol O-methyltransferase |
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| Synonyms: | COMT_RAT | Catechol O-methyltransferase | Catechol-O-methyltransferase | Comt |
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| Type: | Enzyme |
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| Mol. Mass.: | 29594.09 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | n/a |
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| Residue: | 264 |
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| Sequence: | MPLAAVSLGLLLLALLLLLRHLGWGLVTIFWFEYVLQPVHNLIMGDTKEQRILRYVQQNA
KPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMA
RLLQPGARLLTMEMNPDYAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDM
VFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSY
LEYMKVVDGLEKAIYQGPSSPDKS
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| BDBM50028548 |
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| n/a |
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| Name | BDBM50028548 |
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| Synonyms: | 1H-indole-5,6-diol | 5,6-dihydroxyindole | CHEMBL92636 | Dopamine lutine |
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| Type | Small organic molecule |
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| Emp. Form. | C8H7NO2 |
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| Mol. Mass. | 149.1467 |
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| SMILES | Oc1cc2cc[nH]c2cc1O |
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| Structure | 
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