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TargetTumor necrosis factor receptor superfamily member 16
LigandBDBM50029494
Substrate/Competitorn/a
Meas. Tech.ChEMBL_144433 (CHEMBL753643)
IC50 2300±n/a nM
Citation Jaen, JC; Laborde, E; Bucsh, RA; Caprathe, BW; Sorenson, RJ; Fergus, J; Spiegel, K; Marks, J; Dickerson, MR; Davis, RE Kynurenic acid derivatives inhibit the binding of nerve growth factor (NGF) to the low-affinity p75 NGF receptor. J Med Chem38:4439-45 (1995) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Tumor necrosis factor receptor superfamily member 16
Name:Tumor necrosis factor receptor superfamily member 16
Synonyms:CD_antigen=CD271 | Gp80-LNGFR | Low affinity neurotrophin receptor p75NTR | Low-affinity nerve growth factor receptor | NGF receptor | NGFR | TNFRSF16 | TNR16_HUMAN | Tumor necrosis factor receptor superfamily member 16 | p75 ICD
Type:PROTEIN
Mol. Mass.:45159.83
Organism:Homo sapiens (Human)
Description:ChEMBL_346884
Residue:427
Sequence:
MGAGATGRAMDGPRLLLLLLLGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGAN
QTVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAPCVEADDAVCRCAYGYYQDETTG
RCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDTERQLREC
TRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAGVVTTVMGSSQ
PVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANSRPVNQTPPPEGEK
LHSDSGISVDSQSLHDQQPHTQTASGQALKGDGGLYSSLPPAKREEVEKLLNGSAGDTWR
HLAGELGYQPEHIDSFTHEACPVRALLASWATQDSATLDALLAALRRIQRADLVESLCSE
STATSPV
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  Blast E-value cutoff:
BDBM50029494
n/a
NameBDBM50029494
Synonyms:2-Methyl-7-oxo-4,7-dihydro-thieno[3,2-b]pyridine-3,5-dicarboxylic acid 3-methyl ester | CHEMBL342150
TypeSmall organic molecule
Emp. Form.C11H9NO5S
Mol. Mass.267.258
SMILESCOC(=O)c1c(C)sc2c(O)cc(nc12)C(O)=O
Structure
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