| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidylglycine alpha-amidating monooxygenase |
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| Ligand | BDBM50030363 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_154488 (CHEMBL765265) |
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| IC50 | 18±n/a nM |
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| Citation |  Erion, MD; Tan, J; Wong, M; Jeng, AY Inhibition of peptidylglycine alpha-amidating monooxygenase by N-substituted homocysteine analogs. J Med Chem37:4430-7 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidylglycine alpha-amidating monooxygenase |
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| Name: | Peptidylglycine alpha-amidating monooxygenase |
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| Synonyms: | AMD_RAT | Pam | Peptidyl-glycine alpha-amidating monooxygenase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 108665.78 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_536304 |
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| Residue: | 976 |
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| Sequence: | MAGRARSGLLLLLLGLLALQSSCLAFRSPLSVFKRFKETTRSFSNECLGTIGPVTPLDAS
DFALDIRMPGVTPKESDTYFCMSMRLPVDEEAFVIDFKPRASMDTVHHMLLFGCNMPSST
GSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFR
DNHKDCSGVSVHLTRVPQPLIAGMYLMMSVDTVIPPGEKVVNADISCQYKMYPMHVFAYR
VHTHHLGKVVSGYRVRNGQWTLIGRQNPQLPQAFYPVEHPVDVTFGDILAARCVFTGEGR
TEATHIGGTSSDEMCNLYIMYYMEAKYALSFMTCTKNVAPDMFRTIPAEANIPIPVKPDM
VMMHGHHKEAENKEKSALMQQPKQGEEEVLEQGDFYSLLSKLLGEREDVHVHKYNPTEKT
ESGSDLVAEIANVVQKKDLGRSDAREGAEHEEWGNAILVRDRIHRFHQLESTLRPAESRA
FSFQQPGEGPWEPEPSGDFHVEEELDWPGVYLLPGQVSGVALDSKNNLVIFHRGDHVWDG
NSFDSKFVYQQRGLGPIEEDTILVIDPNNAEILQSSGKNLFYLPHGLSIDTDGNYWVTDV
ALHQVFKLDPHSKEGPLLILGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIV
QFSPSGKFVTQWGEESSGSSPRPGQFSVPHSLALVPHLDQLCVADRENGRIQCFKTDTKE
FVREIKHASFGRNVFAISYIPGFLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKPVRK
HFDMPHDIVASEDGTVYIGDAHTNTVWKFTLTEKMEHRSVKKAGIEVQEIKEAEAVVEPK
VENKPTSSELQKMQEKQKLSTEPGSGVSVVLITTLLVIPVLVLLAIVMFIRWKKSRAFGD
HDRKLESSSGRVLGRFRGKGSGGLNLGNFFASRKGYSRKGFDRVSTEGSDQEKDEDDGTE
SEEEYSAPLPKPAPSS
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| BDBM50030363 |
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| n/a |
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| Name | BDBM50030363 |
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| Synonyms: | (S)-2-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-4-mercapto-butyric acid | CHEMBL277080 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24N2O5S |
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| Mol. Mass. | 416.491 |
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| SMILES | OC(=O)[C@H](CCS)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 |
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| Structure | 
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