| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Peptidylglycine alpha-amidating monooxygenase |
|---|
| Ligand | BDBM50030369 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_154488 (CHEMBL765265) |
|---|
| IC50 | 4000±n/a nM |
|---|
| Citation |  Erion, MD; Tan, J; Wong, M; Jeng, AY Inhibition of peptidylglycine alpha-amidating monooxygenase by N-substituted homocysteine analogs. J Med Chem37:4430-7 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Peptidylglycine alpha-amidating monooxygenase |
|---|
| Name: | Peptidylglycine alpha-amidating monooxygenase |
|---|
| Synonyms: | AMD_RAT | Pam | Peptidyl-glycine alpha-amidating monooxygenase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 108665.78 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_536304 |
|---|
| Residue: | 976 |
|---|
| Sequence: | MAGRARSGLLLLLLGLLALQSSCLAFRSPLSVFKRFKETTRSFSNECLGTIGPVTPLDAS
DFALDIRMPGVTPKESDTYFCMSMRLPVDEEAFVIDFKPRASMDTVHHMLLFGCNMPSST
GSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFR
DNHKDCSGVSVHLTRVPQPLIAGMYLMMSVDTVIPPGEKVVNADISCQYKMYPMHVFAYR
VHTHHLGKVVSGYRVRNGQWTLIGRQNPQLPQAFYPVEHPVDVTFGDILAARCVFTGEGR
TEATHIGGTSSDEMCNLYIMYYMEAKYALSFMTCTKNVAPDMFRTIPAEANIPIPVKPDM
VMMHGHHKEAENKEKSALMQQPKQGEEEVLEQGDFYSLLSKLLGEREDVHVHKYNPTEKT
ESGSDLVAEIANVVQKKDLGRSDAREGAEHEEWGNAILVRDRIHRFHQLESTLRPAESRA
FSFQQPGEGPWEPEPSGDFHVEEELDWPGVYLLPGQVSGVALDSKNNLVIFHRGDHVWDG
NSFDSKFVYQQRGLGPIEEDTILVIDPNNAEILQSSGKNLFYLPHGLSIDTDGNYWVTDV
ALHQVFKLDPHSKEGPLLILGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIV
QFSPSGKFVTQWGEESSGSSPRPGQFSVPHSLALVPHLDQLCVADRENGRIQCFKTDTKE
FVREIKHASFGRNVFAISYIPGFLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKPVRK
HFDMPHDIVASEDGTVYIGDAHTNTVWKFTLTEKMEHRSVKKAGIEVQEIKEAEAVVEPK
VENKPTSSELQKMQEKQKLSTEPGSGVSVVLITTLLVIPVLVLLAIVMFIRWKKSRAFGD
HDRKLESSSGRVLGRFRGKGSGGLNLGNFFASRKGYSRKGFDRVSTEGSDQEKDEDDGTE
SEEEYSAPLPKPAPSS
|
|
|
|---|
| BDBM50030369 |
|---|
| n/a |
|---|
| Name | BDBM50030369 |
|---|
| Synonyms: | CHEMBL344411 | {(S)-2-[(R)-2-tert-Butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-3-phenyl-propionylamino}-acetic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H31N3O7 |
|---|
| Mol. Mass. | 485.5295 |
|---|
| SMILES | CC(C)(C)OC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
