| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Kallikrein-1 |
|---|
| Ligand | BDBM50031708 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_92381 (CHEMBL701594) |
|---|
| IC50 | 15700±n/a nM |
|---|
| Citation |  Senokuchi, K; Nakai, H; Nakayama, Y; Odagaki, Y; Sakaki, K; Kato, M; Maruyama, T; Miyazaki, T; Ito, H; Kamiyasu, K New orally active serine protease inhibitors. J Med Chem38:2521-3 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Kallikrein-1 |
|---|
| Name: | Kallikrein-1 |
|---|
| Synonyms: | KLK1 | KLK1_HUMAN | Kallikrein 1 | Kallikrein-1 | Kidney/pancreas/salivary gland kallikrein | Tissue kallikrein |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 28874.69 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P06870 |
|---|
| Residue: | 262 |
|---|
| Sequence: | MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV
LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD
LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL
PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK
PSVAVRVLSYVKWIEDTIAENS
|
|
|
|---|
| BDBM50031708 |
|---|
| n/a |
|---|
| Name | BDBM50031708 |
|---|
| Synonyms: | 4-[(E)-2-(Allyl-ethoxycarbonylmethyl-carbamoyl)-propenyl]-benzoic acid 4-carbamimidoyl-phenyl ester; compound with methanesulfonic acid | CHEMBL85136 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H27N3O5 |
|---|
| Mol. Mass. | 449.499 |
|---|
| SMILES | CCOC(=O)CN(CC=C)C(=O)C(\C)=C\c1ccc(cc1)C(=O)Oc1ccc(cc1)C(N)=N |
|---|
| Structure | 
|
|---|
Search and Browse
