| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine protease 1 |
|---|
| Ligand | BDBM50031709 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_213240 (CHEMBL821450) |
|---|
| IC50 | 55.0±n/a nM |
|---|
| Citation |  Senokuchi, K; Nakai, H; Nakayama, Y; Odagaki, Y; Sakaki, K; Kato, M; Maruyama, T; Miyazaki, T; Ito, H; Kamiyasu, K New orally active serine protease inhibitors. J Med Chem38:2521-3 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine protease 1 |
|---|
| Name: | Serine protease 1 |
|---|
| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 26557.80 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P07477 |
|---|
| Residue: | 247 |
|---|
| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
|
|
|
|---|
| BDBM50031709 |
|---|
| n/a |
|---|
| Name | BDBM50031709 |
|---|
| Synonyms: | 4-Guanidino-benzoic acid 4-carboxymethyl-phenyl ester; compound with methanesulfonic acid | CHEMBL433135 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H15N3O4 |
|---|
| Mol. Mass. | 313.308 |
|---|
| SMILES | [#7]\[#6](-[#7])=[#7]/c1ccc(cc1)-[#6](=O)-[#8]-c1ccc(-[#6]-[#6](-[#8])=O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
