| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor alpha |
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| Ligand | BDBM50032223 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_197382 (CHEMBL799701) |
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| EC50 | >0.001±n/a nM |
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| Citation |  Beard, RL; Chandraratna, RA; Colon, DF; Gillett, SJ; Henry, E; Marler, DK; Song, T; Denys, L; Garst, ME; Arefieg, T Synthesis and structure-activity relationships of stilbene retinoid analogs substituted with heteroaromatic carboxylic acids. J Med Chem38:2820-9 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor alpha |
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| Name: | Retinoic acid receptor alpha |
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| Synonyms: | NR1B1 | Nuclear receptor subfamily 1 group B member 1 | RAR-alpha | RARA | RARA_HUMAN | Retinoic acid receptor alpha | Retinoic acid receptor alpha/Retinoid X receptor alpha | Retinoid X receptor gamma/retinoic acid receptor alpha | Retinoid receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50778.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1466191 |
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| Residue: | 462 |
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| Sequence: | MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
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| BDBM50032223 |
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| n/a |
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| Name | BDBM50032223 |
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| Synonyms: | 4-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-thiophene-2-carboxylic acid | CHEMBL316336 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H28O2S |
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| Mol. Mass. | 368.532 |
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| SMILES | C\C(=C/c1csc(c1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C |
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| Structure | 
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