| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-beta |
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| Ligand | BDBM50032671 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_197067 (CHEMBL806656) |
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| Kd | 3±n/a nM |
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| Citation |  Boehm, MF; Zhang, L; Zhi, L; McClurg, MR; Berger, E; Wagoner, M; Mais, DE; Suto, CM; Davies, JA; Heyman, RA Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells. J Med Chem38:3146-55 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor RXR-beta |
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| Name: | Retinoic acid receptor RXR-beta |
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| Synonyms: | Nr2b2 | RXRB_MOUSE | Retinoid X receptor beta | Rxrb |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55877.78 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_196588 |
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| Residue: | 520 |
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| Sequence: | MSWATRPPFLPPRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAGEQQALEP
EPGEAGRDGMGDSGRDSRSPDSSSPNPLSQGIRPSSPPGPPLTPSAPPPPMPPPPLGSPF
PVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPP
PPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQ
RNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGDGAGGAPEEMPVDRILEAELAVEQ
KSDQGVEGPGATGGGGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLR
AGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRM
DKTELGCLRAIILFNPDAKGLSNPGEVEILREKVYASLETYCKQKYPEQQGRFAKLLLRL
PALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
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| BDBM50032671 |
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| n/a |
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| Name | BDBM50032671 |
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| Synonyms: | 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CYCLOPROPYL]PYRIDINE-3-CARBOXYLIC ACID | 6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-cyclopropyl]-nicotinic acid | CHEMBL288436 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H29NO2 |
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| Mol. Mass. | 363.4926 |
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| SMILES | Cc1cc2c(cc1C1(CC1)c1ccc(cn1)C(O)=O)C(C)(C)CCC2(C)C |
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| Structure | 
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