| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-gamma |
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| Ligand | BDBM50032665 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_197220 (CHEMBL798968) |
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| EC50 | 600±n/a nM |
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| Citation |  Boehm, MF; Zhang, L; Zhi, L; McClurg, MR; Berger, E; Wagoner, M; Mais, DE; Suto, CM; Davies, JA; Heyman, RA Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells. J Med Chem38:3146-55 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor RXR-gamma |
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| Name: | Retinoic acid receptor RXR-gamma |
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| Synonyms: | Nr2b3 | RXRG_MOUSE | Retinoid X receptor gamma | Rxrg |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50900.28 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_196589 |
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| Residue: | 463 |
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| Sequence: | MYGNYSHFMKFPTGFGGSPGHTGSTSMSPSVALPTGKPMDSHPSYTDTPVSAPRTLSAVG
TPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPG
IGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKD
CLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECASSSHEDMPVERIL
EAELAVEPKTESYGDMNVENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVI
LLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKD
MQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLL
LRLPALRSIGLKCLEHLFFFKLIGDTPIDSFLMEMLETPLQIT
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| BDBM50032665 |
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| n/a |
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| Name | BDBM50032665 |
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| Synonyms: | 4-[1-(3,5,5-Trimethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acid | CHEMBL108402 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24O2 |
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| Mol. Mass. | 320.4248 |
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| SMILES | Cc1cc2c(CCCC2(C)C)cc1C(=C)c1ccc(cc1)C(O)=O |
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| Structure | 
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