Ki Summary

Reaction Details

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Target

Interleukin-2

Ligand

BDBM50033058

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_89079 (CHEMBL698590)

IC50

70±n/a nM

Citation

Mikol, V; Papageorgiou, C; Borer, X The role of water molecules in the structure-based design of (5-hydroxynorvaline)-2-cyclosporin: synthesis, biological activity, and crystallographic analysis with cyclophilin A. J Med Chem38:3361-7 (1995) [PubMed]

More Info.:

Get all data from this article, Assay Method

Interleukin-2

Name:

Interleukin-2

Synonyms:

IL2_MOUSE | Il-2 | Il2 | T-cell growth factor | TCGF

Type:

PROTEIN

Mol. Mass.:

19394.78

Organism:

Mus musculus

Description:

ChEMBL_89079

Residue:

169

Sequence:

MYSMQLASCVTLTLVLLVNSAPTSSSTSSSTAEAQQQQQQQQQQQQHLEQLLMDLQELLS
RMENYRNLKLPRMLTFKFYLPKQATELKDLQCLEDELGPLRHVLDLTQSKSFQLEDAENF
ISNIRVTVVKLKGSDNTFECQFDDESATVVDFLRRWIAFCQSIISTSPQ

BDBM50033058

n/a

Name

BDBM50033058

Synonyms:

33-(1-Hydroxy-2-methyl-hex-4-enyl)-30-(3-hydroxy-propyl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31undecaaza-cyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone | CHEMBL415597

Type

Small organic molecule

Emp. Form.

C63H113N11O13

Mol. Mass.

1232.6372

SMILES

C\C=C\C[C@@H](C)[C@@H](O)[C@H]1N(C)C(=O)[C@@H](C(C)C)N(C)C(=O)[C@@H](CC(C)C)N(C)C(=O)[C@@H](CC(C)C)N(C)C(=O)[C@H](C)NC(=O)[C@@H](C)NC(=O)[C@@H](CC(C)C)N(C)C(=O)[C@H](NC(=O)[C@@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@@H](CCCO)NC1=O)C(C)C

Structure