| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-beta |
|---|
| Ligand | BDBM50033076 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_197075 (CHEMBL806663) |
|---|
| EC50 | 33±n/a nM |
|---|
| Citation |  Dawson, MI; Jong, L; Hobbs, PD; Cameron, JF; Chao, WR; Pfahl, M; Lee, MO; Shroot, B; Pfahl, M Conformational effects on retinoid receptor selectivity. 2. Effects of retinoid bridging group on retinoid X receptor activity and selectivity. J Med Chem38:3368-83 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinoic acid receptor RXR-beta |
|---|
| Name: | Retinoic acid receptor RXR-beta |
|---|
| Synonyms: | NR2B2 | Nuclear receptor subfamily 2 group B member 2 | RXRB | RXRB_HUMAN | Retinoic acid receptor RXR-beta | Retinoid X receptor beta | Retinoid receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 56932.89 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_39045 |
|---|
| Residue: | 533 |
|---|
| Sequence: | MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQT
PEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPP
PPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVK
PPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYS
CRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMP
VDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHF
SSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRV
LTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYP
EQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
|
|
|
|---|
| BDBM50033076 |
|---|
| n/a |
|---|
| Name | BDBM50033076 |
|---|
| Synonyms: | 5-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-thiophene-2-carboxylic acid | CHEMBL111983 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H26O2S |
|---|
| Mol. Mass. | 354.506 |
|---|
| SMILES | Cc1cc2c(cc1C(=C)c1ccc(s1)C(O)=O)C(C)(C)CCC2(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
