| Reaction Details |
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 | Report a problem with these data |
| Target | C5a anaphylatoxin chemotactic receptor 1 |
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| Ligand | BDBM50008381 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_157769 (CHEMBL767672) |
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| EC50 | 900±n/a nM |
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| Citation |  Sanderson, SD; Kirnarsky, L; Sherman, SA; Vogen, SM; Prakash, O; Ember, JA; Finch, AM; Taylor, SM Decapeptide agonists of human C5a: the relationship between conformation and neutrophil response. J Med Chem38:3669-75 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| C5a anaphylatoxin chemotactic receptor 1 |
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| Name: | C5a anaphylatoxin chemotactic receptor 1 |
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| Synonyms: | C5AR | C5AR1 | C5AR1_HUMAN | C5R1 | C5a anaphylatoxin chemotactic receptor | C5a anaphylatoxin chemotactic receptor (C5aR) | C5a-R | CD_antigen=CD88 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39347.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21730 |
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| Residue: | 350 |
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| Sequence: | MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVW
VTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNM
YASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREE
YFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKT
LKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIY
VVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
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| BDBM50008381 |
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| n/a |
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| Name | BDBM50008381 |
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| Synonyms: | CHEMBL441393 | H-Ile-Ser-Phe-Lys-AspMet-GIn-Leu-Gly-Arg-OH | Ile-Ser-Phe-Lys-Asp-Met-Gln-Leu-Gly-Arg |
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| Type | Small organic molecule |
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| Emp. Form. | C52H87N15O15S |
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| Mol. Mass. | 1194.404 |
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| SMILES | CC[C@H](C)[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(O)=O |
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| Structure | 
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