| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM50033644 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_136067 |
|---|
| IC50 | 32±n/a nM |
|---|
| Citation |  Sebastian, A; Bidlack, JM; Jiang, Q; Deecher, D; Teitler, M; Glick, SD; Archer, S 14 beta-[(p-nitrocinnamoyl)amino]morphinones, 14 beta-[(p-nitrocinnamoyl)amino]-7,8-dihydromorphinones, and their codeinone analogues: synthesis and receptor activity. J Med Chem36:3154-60 (1993) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | MOR-1 | Mu opioid receptor | OPIATE Mu | OPRM1 | OPRM_BOVIN |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 45038.37 |
|---|
| Organism: | CALF |
|---|
| Description: | OPIATE Mu 2 0 CALF::P79350 |
|---|
| Residue: | 401 |
|---|
| Sequence: | MDSGAVPTNASNCTDPFTHPSSCSPAPSPSSWVNFSHLEGNLSDPCGPNRTELGGSDRLC
PSAGSPSMITAIIIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALA
TSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALD
LRTPRNAKIINICNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVF
IFAFIMPILIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIH
IYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSST
IEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETTPLP
|
|
|
|---|
| BDBM50033644 |
|---|
| n/a |
|---|
| Name | BDBM50033644 |
|---|
| Synonyms: | 1N-[4-cyclopropylmethyl-10-methoxy-13-methyl-14-oxo-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraen-17-yl]-4-(4-nitrophenyl)-(Z)-2-butenamide | CHEMBL327111 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H33N3O6 |
|---|
| Mol. Mass. | 543.6102 |
|---|
| SMILES | COc1ccc2CC3N(CC4CC4)CCC45c2c1O[C@@]4(C)C(=O)CC[C@@]35NC(=O)\C=C\c1ccc(cc1)[N+]([O-])=O |TLB:26:25:16.5.6:8.14.13,THB:9:8:25:16.5.6,17:16:25:8.14.13| |
|---|
| Structure | 
|
|---|
Search and Browse
