| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM50033652 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_136067 |
|---|
| IC50 | 39.1±n/a nM |
|---|
| Citation |  Sebastian, A; Bidlack, JM; Jiang, Q; Deecher, D; Teitler, M; Glick, SD; Archer, S 14 beta-[(p-nitrocinnamoyl)amino]morphinones, 14 beta-[(p-nitrocinnamoyl)amino]-7,8-dihydromorphinones, and their codeinone analogues: synthesis and receptor activity. J Med Chem36:3154-60 (1993) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | MOR-1 | Mu opioid receptor | OPIATE Mu | OPRM1 | OPRM_BOVIN |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 45038.37 |
|---|
| Organism: | CALF |
|---|
| Description: | OPIATE Mu 2 0 CALF::P79350 |
|---|
| Residue: | 401 |
|---|
| Sequence: | MDSGAVPTNASNCTDPFTHPSSCSPAPSPSSWVNFSHLEGNLSDPCGPNRTELGGSDRLC
PSAGSPSMITAIIIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALA
TSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALD
LRTPRNAKIINICNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVF
IFAFIMPILIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIH
IYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSST
IEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETTPLP
|
|
|
|---|
| BDBM50033652 |
|---|
| n/a |
|---|
| Name | BDBM50033652 |
|---|
| Synonyms: | 1N-[4-cyclopropylmethyl-10-methoxy-14-oxo-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-17-yl]-4-(4-nitrophenyl)-(Z)-2-butenamide | CHEMBL610885 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H31N3O6 |
|---|
| Mol. Mass. | 529.5836 |
|---|
| SMILES | [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@]5(CCC2=O)NC(=O)\C=C\c1ccc(cc1)[N+]([O-])=O)ccc3OC |r,THB:10:9:5.4.6:17| |
|---|
| Structure | 
|
|---|
Search and Browse
