| Reaction Details |
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 | Report a problem with these data |
| Target | Trypsin |
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| Ligand | BDBM50034580 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_212372 |
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| Ki | 0.44±n/a nM |
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| Citation |  Deadman JJ; Elgendy S; Goodwin CA; Green D; Baban JA; Patel G; Skordalakes E; Chino N; Claeson G; Kakkar VV Characterization of a class of peptide boronates with neutral P1 side chains as highly selective inhibitors of thrombin. J Med Chem 38:1511-22 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Trypsin |
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| Name: | Trypsin I |
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| Synonyms: | Beta-Trypsin | Cationic trypsin | Trypsin I |
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| Type: | Enzyme |
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| Mol. Mass.: | 25790.52 |
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| Organism: | Bos taurus (bovine) |
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| Description: | P00760 |
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| Residue: | 246 |
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| Sequence: | MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN
SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT
SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK
QTIASN
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| BDBM50034580 |
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| n/a |
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| Name | BDBM50034580 |
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| Synonyms: | CHEMBL418050 | Peptide boronate |
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| Type | Small organic molecule |
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| Emp. Form. | C46H52BN3O6 |
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| Mol. Mass. | 753.733 |
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| SMILES | CC1(C)C2CC1[C@]1(C)OB(O[C@@H]1C2)C(Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCc1ccccc1)C(c1ccccc1)c1ccccc1 |
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| Structure | 
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