| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50034710 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_85848 (CHEMBL693575) |
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| Ki | >2000±n/a nM |
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| Citation |  Shih, NY; Lupo, AT; Aslanian, R; Orlando, S; Piwinski, JJ; Green, MJ; Ganguly, AK; Clark, MA; Tozzi, S; Kreutner, W A novel pyrrolidine analog of histamine as a potent, highly selective histamine H3 receptor agonist. J Med Chem38:1593-9 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48753.61 |
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| Organism: | GUINEA PIG |
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| Description: | HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35 |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAF
VADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCT
SSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSG
GSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGARE
AGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHSSLEHCWK
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| BDBM50034710 |
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| n/a |
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| Name | BDBM50034710 |
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| Synonyms: | (1R,2S)-2-(1H-Imidazol-4-yl)-1-methyl-cyclohexylamine | CHEMBL289123 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H17N3 |
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| Mol. Mass. | 179.2621 |
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| SMILES | C[C@@]1(N)CCCC[C@@H]1c1cnc[nH]1 |
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| Structure | 
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