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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Muscarinic acetylcholine receptor M2 | ||
| Ligand | BDBM50034871 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_138162 (CHEMBL748226) | ||
| Ki | 7.6±n/a nM | ||
| Citation |  Kiesewetter, DO; Silverton, JV; Eckelman, WC Syntheses and biological properties of chiral fluoroalkyl quinuclidinyl benzilates. J Med Chem38:1711-9 (1995) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Muscarinic acetylcholine receptor M2 | |||
| Name: | Muscarinic acetylcholine receptor M2 | ||
| Synonyms: | ACM2_RAT | Cholinergic, muscarinic M2 | Chrm-2 | Chrm2 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 51555.53 | ||
| Organism: | RAT | ||
| Description: | P10980 | ||
| Residue: | 466 | ||
| Sequence: |
| ||
| BDBM50034871 | |||
| n/a | |||
| Name | BDBM50034871 | ||
| Synonyms: | (R)-[4-(2-Fluoro-ethyl)-phenyl]-hydroxy-phenyl-acetic acid 1-aza-bicyclo[2.2.2]oct-3-yl ester | CHEMBL49576 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H26FNO3 | ||
| Mol. Mass. | 383.4558 | ||
| SMILES | O[C@](C(=O)OC1CN2CCC1CC2)(c1ccccc1)c1ccc(CCF)cc1 |wU:1.1,wD:1.0,THB:4:5:9.8:11.12,(7.07,-6.11,;6.32,-7.44,;7.84,-8,;8.09,-9.51,;9.03,-7.03,;10.47,-7.55,;11.24,-6.33,;12.94,-5.56,;14.5,-6.49,;13.7,-7.64,;12.1,-6.68,;12.1,-5.3,;12.94,-4.49,;5.53,-8.77,;3.99,-8.74,;3.19,-10.05,;3.96,-11.4,;5.5,-11.4,;6.27,-10.08,;4.98,-6.67,;3.64,-7.44,;2.32,-6.67,;2.32,-5.13,;.97,-4.36,;.97,-2.82,;-.34,-2.05,;3.64,-4.34,;4.98,-5.11,)| | ||
| Structure | 
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