Ki Summary

Reaction Details

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Target

Muscarinic receptor M1

Ligand

BDBM50010096

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_138130 (CHEMBL872660)

0.22±n/a nM

Citation

Kiesewetter, DO; Silverton, JV; Eckelman, WC Syntheses and biological properties of chiral fluoroalkyl quinuclidinyl benzilates. J Med Chem38:1711-9 (1995) [PubMed]

More Info.:

Get all data from this article, Assay Method

Muscarinic receptor M1

Name:

Muscarinic receptor M1

Synonyms:

Muscarinic acetylcholine receptor M1

Type:

PROTEIN

Mol. Mass.:

15022.43

Organism:

Bos taurus

Description:

ChEMBL_140161

Residue:

139

Sequence:

ETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRTPRLLQAYS
WKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPAKQPPRSSPNTVKRPTRKG
RERAGKGQKPRGKEQLAKR

BDBM50010096

n/a

Name

BDBM50010096

Synonyms:

CHEMBL12980 | Hydroxy-diphenyl-acetic acid 1-aza-bicyclo[2.2.2]oct-3-yl ester | Hydroxy-diphenyl-acetic acid 1-aza-bicyclo[2.2.2]oct-3-yl ester(QNB) | Hydroxy-diphenyl-acetic acid 1-aza-bicyclo[2.2.2]oct-3-yl ester(R)-(-)-(QNB)

Type

Small organic molecule

Emp. Form.

C21H23NO3

Mol. Mass.

337.4122

SMILES

OC(C(=O)OC1CN2CCC1CC2)(c1ccccc1)c1ccccc1 |(5.41,-4.43,;4.65,-5.78,;6.2,-5.78,;6.97,-7.12,;6.97,-4.45,;8.52,-4.1,;8.52,-2.56,;9.86,-1.78,;11.19,-2.56,;11.19,-4.1,;9.86,-4.88,;9.09,-3.78,;9.09,-2.9,;3.1,-5.81,;2.36,-7.19,;.82,-7.2,;.01,-5.88,;.78,-4.52,;2.32,-4.49,;4.65,-7.23,;3.39,-7.96,;3.38,-9.41,;4.64,-10.15,;5.91,-9.42,;5.91,-7.97,)|

Structure