| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50035325 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_63066 (CHEMBL673633) |
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| Ki | 5.9±n/a nM |
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| Citation |  Stjernlöf, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikström, H Structure-activity relationships in the 8-amino-6,7,8,9-tetrahydro-3H-benz[e]indole ring system. 1. Effects of substituents in the aromatic system on serotonin and dopamine receptor subtypes. J Med Chem38:2202-16 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50035325 |
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| n/a |
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| Name | BDBM50035325 |
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| Synonyms: | (4-Fluoro-1-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-dipropyl-amine | CHEMBL71663 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H31FN2 |
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| Mol. Mass. | 330.4826 |
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| SMILES | CCCN(CCC)C1CCc2cc(F)c3[nH]cc(CCC)c3c2C1 |
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| Structure | 
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