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TargetGag-Pol polyprotein [489-587]
LigandBDBM50036264
Substrate/Competitorn/a
Meas. Tech.ChEMBL_157543 (CHEMBL764927)
Ki 227±n/a nM
Citation Vazquez, MLBryant, MLClare, MDeCrescenzo, GADoherty, EMFreskos, JNGetman, DPHouseman, KAJulien, JAKocan, GP Inhibitors of HIV-1 protease containing the novel and potent (R)-(hydroxyethyl)sulfonamide isostere. J Med Chem38:581-4 (1995) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50036264
n/a
NameBDBM50036264
Synonyms:CHEMBL154600 | {(1S,2R)-1-Benzyl-3-[(2-chloro-benzenesulfonyl)-(3-methyl-butyl)-amino]-2-hydroxy-propyl}-carbamic acid benzyl ester
TypeSmall organic molecule
Emp. Form.C29H35ClN2O5S
Mol. Mass.559.117
SMILESCC(C)CCN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)S(=O)(=O)c1ccccc1Cl
Structure
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