| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
|---|
| Ligand | BDBM50016013 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_58506 (CHEMBL672001) |
|---|
| Ki | 20.4±n/a nM |
|---|
| Citation |  Hedberg, MH; Johansson, AM; Nordvall, G; Yliniemelä, A; Li, HB; Martin, AR; Hjorth, S; Unelius, L; Sundell, S; Hacksell, U (R)-11-hydroxy- and (R)-11-hydroxy-10-methylaporphine: synthesis, pharmacology, and modeling of D2A and 5-HT1A receptor interactions. J Med Chem38:647-58 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(1A) dopamine receptor |
|---|
| Name: | D(1A) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 49429.75 |
|---|
| Organism: | RAT |
|---|
| Description: | P18901 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
|
|
|
|---|
| BDBM50016013 |
|---|
| n/a |
|---|
| Name | BDBM50016013 |
|---|
| Synonyms: | (R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol | 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol | CHEMBL119455 | R-(-)-11-hydroxy-aporphine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H17NO |
|---|
| Mol. Mass. | 251.323 |
|---|
| SMILES | CN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 |
|---|
| Structure | 
|
|---|
Search and Browse
