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TargetGag-Pol polyprotein [489-587]
LigandBDBM50037127
Substrate/Competitorn/a
Meas. Tech.ChEMBL_157870 (CHEMBL879227)
Ki 370±n/a nM
Citation Thompson, SKMurthy, KHZhao, BWinborne, EGreen, DWFisher, SMDesJarlais, RLTomaszek, TAMeek, TDGleason, JG Rational design, synthesis, and crystallographic analysis of a hydroxyethylene-based HIV-1 protease inhibitor containing a heterocyclic P1'--P2' amide bond isostere. J Med Chem37:3100-7 (1994) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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  Blast E-value cutoff:
BDBM50037127
n/a
NameBDBM50037127
Synonyms:CHEMBL104285 | [(1S,2S,4R)-4-(5-Acetyl-1H-imidazol-2-yl)-1-benzyl-2-hydroxy-5-phenyl-pentyl]-carbamic acid tert-butyl ester
TypeSmall organic molecule
Emp. Form.C28H35N3O4
Mol. Mass.477.5952
SMILESCC(=O)c1cnc([nH]1)[C@@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1ccccc1
Structure
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