| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50037674 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_61753 (CHEMBL676060) |
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| IC50 | 141±n/a nM |
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| Citation |  Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT The discovery and structure-activity relationships of 1,2,3,6-tetrahydro-4-phenyl-1-[(arylcyclohexenyl)alkyl]pyridines. Dopamine autoreceptor agonists and potential antipsychotic agents. J Med Chem37:3523-33 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50037674 |
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| n/a |
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| Name | BDBM50037674 |
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| Synonyms: | 1-(3-Phenyl-cyclohex-3-enylmethyl)-4-pyridin-2-yl-piperazine | CHEMBL116205 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27N3 |
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| Mol. Mass. | 333.4699 |
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| SMILES | C(C1CCC=C(C1)c1ccccc1)N1CCN(CC1)c1ccccn1 |c:4| |
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| Structure | 
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