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TargetGag-Pol polyprotein [489-587]
LigandBDBM50407258
Substrate/Competitorn/a
Meas. Tech.ChEMBL_159307 (CHEMBL769360)
IC50 82±n/a nM
Citation Kitchin, JBethell, RCCammack, NDolan, SEvans, DNHolman, SHolmes, DSMcMeekin, PMo, CLNieland, N Synthesis and structure-activity relationships of a series of penicillin-derived HIV proteinase inhibitors: heterocyclic ring systems containing P1' and P2' substituents. J Med Chem37:3707-16 (1994) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50407258
n/a
NameBDBM50407258
Synonyms:CHEMBL2111802
TypeSmall organic molecule
Emp. Form.C42H55N7O7S
Mol. Mass.801.994
SMILESCC(C)(C)NC(=O)[C@H]1CN(CCN1C[C@@H](O)CNC(=O)[C@@H]1N[C@H](SC1(C)C)C(NC(=O)Cc1ccccc1)C(=O)NCc1ccccc1)C(=O)Oc1ccccc1
Structure
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