| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2C |
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| Ligand | BDBM50005257 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2841 (CHEMBL621526) |
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| Ki | 70±n/a nM |
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| Citation |  Glennon, RA; Dukat, M; el-Bermawy, M; Law, H; De los Angeles, J; Teitler, M; King, A; Herrick-Davis, K Influence of amine substituents on 5-HT2A versus 5-HT2C binding of phenylalkyl- and indolylalkylamines. J Med Chem37:1929-35 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2C |
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| Name: | 5-hydroxytryptamine receptor 2C |
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| Synonyms: | 5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2c) | 5HT2C_RAT | 5ht1c | Htr1c | Htr2c | Serotonin (5-HT) receptor | Serotonin receptor 2a and 2c (5HT2A and 5HT2C) |
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| Type: | Enzyme |
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| Mol. Mass.: | 51935.10 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P08909 |
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| Residue: | 460 |
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| Sequence: | MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALS
IVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYV
WPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVW
AISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIY
VLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRG
TMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGY
VCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRH
TNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV
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| BDBM50005257 |
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| n/a |
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| Name | BDBM50005257 |
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| Synonyms: | (+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine | (+)2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine | (+/-)2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine | (-)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine | (-)2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine | 1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine | 2-(2-Methoxy-phenyl)-1-methyl-ethylamine | 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine | 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine((-)-DOB) | 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine((R)-(-)-DOB) | 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine((S)-(+)-DOB) | 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine(DOB) | 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine[R(-)DOB] | 2-(5-Bromo-2,4-dimethoxy-phenyl)-1-methyl-ethylamine | Brolamfetamine | CHEMBL6607 | DOB | Racemic DOB |
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| Type | Small organic molecule |
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| Emp. Form. | C11H16BrNO2 |
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| Mol. Mass. | 274.154 |
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| SMILES | COc1cc(CC(C)N)c(OC)cc1Br |
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| Structure | 
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