| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50039104 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_145681 (CHEMBL754277) |
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| IC50 | >1000±n/a nM |
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| Citation |  Naylor, A; Judd, DB; Scopes, DI; Hayes, AG; Birch, PJ 4-[(Alkylamino)methyl]furo[3,2-c]pyridines: a new series of selective kappa-receptor agonists. J Med Chem37:2138-44 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM50039104 |
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| n/a |
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| Name | BDBM50039104 |
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| Synonyms: | (SS)-2-(3,4-Dichloro-phenyl)-1-[4-(3-hydroxy-pyrrolidin-1-ylmethyl)-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl]-ethanone(GR 91272) | 2-(3,4-Dichloro-phenyl)-1-[(S)-4-((S)-3-hydroxy-pyrrolidin-1-ylmethyl)-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl]-ethanone | CHEMBL67137 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22Cl2N2O3 |
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| Mol. Mass. | 409.306 |
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| SMILES | O[C@H]1CCN(C[C@H]2N(CCc3occc23)C(=O)Cc2ccc(Cl)c(Cl)c2)C1 |
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| Structure | 
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