| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Calpain-2 catalytic subunit |
|---|
| Ligand | BDBM50039994 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_43845 (CHEMBL658507) |
|---|
| Ki | 50±n/a nM |
|---|
| Citation |  Harbeson, SL; Abelleira, SM; Akiyama, A; Barrett, R; Carroll, RM; Straub, JA; Tkacz, JN; Wu, C; Musso, GF Stereospecific synthesis of peptidyl alpha-keto amides as inhibitors of calpain. J Med Chem37:2918-29 (1994) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Calpain-2 catalytic subunit |
|---|
| Name: | Calpain-2 catalytic subunit |
|---|
| Synonyms: | CAN2_BOVIN | CAPN2 | Calpain 2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 79905.09 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_43846 |
|---|
| Residue: | 700 |
|---|
| Sequence: | MAGIAAKLAKDREAAEGLGSHERAVKYLNQDYAALRDECLEAGALFQDPSFPALPSSLGF
KELGPYSSKTRGIEWKRPTEICDNPQFITGGATRTDICQGALGDCWLLAAIASLTLNEEI
LARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL
LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKAPPNLFRIIQKALQKGSLLGC
SIDITSAADSEAITFQKLVKGHAYSVTGAEEVESRGSLQKLIRIRNPWGEVEWTGQWNDN
CPNWNTVDPEVRETLTRQHEDGEFWMSFNDFLRHYSRLEICNLTPDTLTSDSYKKWKLTK
MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDQEDGESGCTFLVGLIQKHRRRQR
KMGEDMHTIGFGIYEVPEELTGQTNIHLSKKFFLTTRARERSDTFINLREVLNRFKLPPG
EYIVVPSTFEPNKDGDFCIRVFSEKKADYQVVDDEIEANIDEIDISEDDIDDGFRRLFAQ
LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL
WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDDLIIDFD
NFVRCLIRLETLFRIFKQLDPENTGMIQLDLISWLSFSVL
|
|
|
|---|
| BDBM50039994 |
|---|
| n/a |
|---|
| Name | BDBM50039994 |
|---|
| Synonyms: | CHEMBL419898 | [(S)-1-(1-Ethylcarbamoyl-butylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H33N3O4 |
|---|
| Mol. Mass. | 391.5044 |
|---|
| SMILES | CCCC(NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)NCC |
|---|
| Structure | 
|
|---|
Search and Browse
