| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-beta |
|---|
| Ligand | BDBM50032675 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_196630 (CHEMBL798184) |
|---|
| EC50 | 24±n/a nM |
|---|
| Citation |  Boehm, MF; Zhang, L; Badea, BA; White, SK; Mais, DE; Berger, E; Suto, CM; Goldman, ME; Heyman, RA Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids. J Med Chem37:2930-41 (1994) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinoic acid receptor RXR-beta |
|---|
| Name: | Retinoic acid receptor RXR-beta |
|---|
| Synonyms: | Nr2b2 | RXRB_MOUSE | Retinoid X receptor beta | Rxrb |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 55877.78 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_196588 |
|---|
| Residue: | 520 |
|---|
| Sequence: | MSWATRPPFLPPRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAGEQQALEP
EPGEAGRDGMGDSGRDSRSPDSSSPNPLSQGIRPSSPPGPPLTPSAPPPPMPPPPLGSPF
PVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPP
PPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQ
RNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGDGAGGAPEEMPVDRILEAELAVEQ
KSDQGVEGPGATGGGGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLR
AGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRM
DKTELGCLRAIILFNPDAKGLSNPGEVEILREKVYASLETYCKQKYPEQQGRFAKLLLRL
PALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
|
|
|
|---|
| BDBM50032675 |
|---|
| n/a |
|---|
| Name | BDBM50032675 |
|---|
| Synonyms: | 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid | BEXAROTENE | CHEMBL1023 | p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H28O2 |
|---|
| Mol. Mass. | 348.4779 |
|---|
| SMILES | Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
