| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50040175 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_578 (CHEMBL615448) |
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| Ki | 0.1±n/a nM |
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| Citation |  Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Centrally acting serotonergic and dopaminergic agents. 1. Synthesis and structure-activity relationships of 2,3,3a,4,5,9b-hexahydro-1H-benz[e]indole derivatives. J Med Chem36:1053-68 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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|
|
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| BDBM50040175 |
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| n/a |
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| Name | BDBM50040175 |
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| Synonyms: | 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol | CHEMBL9979 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H21NO |
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| Mol. Mass. | 231.3333 |
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| SMILES | CCCN1CCC2[C@H]1CCc1cccc(O)c21 |
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| Structure | 
|
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