| Reaction Details |
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 | Report a problem with these data |
| Target | Gastrin-releasing peptide receptor |
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| Ligand | BDBM50040321 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_458 (CHEMBL615688) |
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| IC50 | 7.3±n/a nM |
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| Citation |  Leban, JJ; Landavazo, A; McDermed, JD; Diliberto, EJ; Jansen, M; Stockstill, B; Kull, FC Potent gastrin-releasing peptide (GRP) antagonists derived from GRP (19-27) with a C-terminal DPro psi [CH2NH]Phe-NH2 and N-terminal aromatic residues. J Med Chem37:439-45 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gastrin-releasing peptide receptor |
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| Name: | Gastrin-releasing peptide receptor |
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| Synonyms: | GRP-R | GRP-preferring bombesin receptor | GRPR_MOUSE | Gastrin releasing peptide receptor | Gastrin-releasing peptide receptor | Grpr |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43234.59 |
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| Organism: | MOUSE |
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| Description: | Gastrin-Releasing peptide 0 MOUSE::P21729 |
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| Residue: | 384 |
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| Sequence: | MAPNNCSHLNLDVDPFLSCNDTFNQSLSPPKMDNWFHPGFIYVIPAVYGLIIVIGLIGNI
TLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFI
QLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFS
DLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLAIISVYYYFIARNLIQ
SAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSML
HFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLMNRSHSTGRSTTCMT
SFKSTNPSATFSLINRNICHEGYV
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| BDBM50040321 |
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| n/a |
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| Name | BDBM50040321 |
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| Synonyms: | CHEMBL385805 | PhCH2CH2(CO)His-Trp-Ala-Val-DAla-His-Sta-Phe-NH2 |
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| Type | Small organic molecule |
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| Emp. Form. | C60H78N14O10 |
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| Mol. Mass. | 1155.3491 |
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| SMILES | CC(C)CC(NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCc1ccccc1)C(C)C)C(O)CC(=O)N[C@@H](Cc1ccccc1)C(N)=O |
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| Structure | 
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