| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM904 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_159974 (CHEMBL768121) |
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| Ki | 1670±n/a nM |
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| Citation |  Reddy, MR; Varney, MD; Kalish, V; Viswanadhan, VN; Appelt, K Calculation of relative differences in the binding free energies of HIV1 protease inhibitors: a thermodynamic cycle perturbation approach. J Med Chem37:1145-52 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM904 |
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| n/a |
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| Name | BDBM904 |
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| Synonyms: | (4S,5S)-5-[(2S)-2-[(2S)-2-aminopropanamido]propanamido]-N-(diphenylmethyl)-4-hydroxy-6-phenylhexanamide | 5-(L-Alanyl-L-alanylamino)-4-hydroxy-6-phenylhexanoic Acid Benzhydrylamide | C-terminal inhibitor 2 | CHEMBL15444 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H38N4O4 |
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| Mol. Mass. | 530.6578 |
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| SMILES | C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CCC(=O)NC(c1ccccc1)c1ccccc1 |r| |
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| Structure | 
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