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Target3',5'-cyclic-AMP phosphodiesterase
LigandBDBM50041847
Substrate/Competitorn/a
Meas. Tech.ChEMBL_157209 (CHEMBL768860)
IC50 16±n/a nM
Citation Ashton, MJCook, DCFenton, GKarlsson, JAPalfreyman, MNRaeburn, DRatcliffe, AJSouness, JEThurairatnam, SVicker, N Selective type IV phosphodiesterase inhibitors as antiasthmatic agents. The syntheses and biological activities of 3-(cyclopentyloxy)-4-methoxybenzamides and analogues. J Med Chem37:1696-703 (1994) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
3',5'-cyclic-AMP phosphodiesterase
Name:3',5'-cyclic-AMP phosphodiesterase
Synonyms:Phosphodiesterase 4A
Type:PROTEIN
Mol. Mass.:13615.65
Organism:Sus scrofa
Description:ChEMBL_155848
Residue:118
Sequence:
PWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVDIPSPTMKDHEKQQ
APRQRPSQQPPPPGPQFQPMSQITGVKKLMHSSSLNEDSSIPRFGVKTDQEELLAQEL
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  Blast E-value cutoff:
BDBM50041847
n/a
NameBDBM50041847
Synonyms:CHEMBL295976 | N-(3-Chloro-pyridin-4-yl)-3-cyclopentyloxy-4-methoxy-benzamide
TypeSmall organic molecule
Emp. Form.C18H19ClN2O3
Mol. Mass.346.808
SMILESCOc1ccc(cc1OC1CCCC1)C(=O)Nc1ccncc1Cl
Structure
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