| Reaction Details |
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 | Report a problem with these data |
| Target | 3',5'-cyclic-AMP phosphodiesterase |
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| Ligand | BDBM50041880 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_157209 (CHEMBL768860) |
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| IC50 | 400±n/a nM |
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| Citation |  Ashton, MJ; Cook, DC; Fenton, G; Karlsson, JA; Palfreyman, MN; Raeburn, D; Ratcliffe, AJ; Souness, JE; Thurairatnam, S; Vicker, N Selective type IV phosphodiesterase inhibitors as antiasthmatic agents. The syntheses and biological activities of 3-(cyclopentyloxy)-4-methoxybenzamides and analogues. J Med Chem37:1696-703 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 3',5'-cyclic-AMP phosphodiesterase |
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| Name: | 3',5'-cyclic-AMP phosphodiesterase |
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| Synonyms: | Phosphodiesterase 4A |
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| Type: | PROTEIN |
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| Mol. Mass.: | 13615.65 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_155848 |
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| Residue: | 118 |
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| Sequence: | PWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVDIPSPTMKDHEKQQ
APRQRPSQQPPPPGPQFQPMSQITGVKKLMHSSSLNEDSSIPRFGVKTDQEELLAQEL
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| BDBM50041880 |
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| n/a |
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| Name | BDBM50041880 |
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| Synonyms: | 3-Cyclopentyloxy-N-(2,6-dichloro-6H-pyrimidin-1-yl)-4-methoxy-benzamide | CHEMBL298792 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H19Cl2N3O3 |
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| Mol. Mass. | 384.257 |
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| SMILES | COc1ccc(cc1OC1CCCC1)C(=O)NN1C(Cl)C=CN=C1Cl |c:22,24| |
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| Structure | 
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