| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin B |
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| Ligand | BDBM50042411 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_47386 |
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| pH | 5.2±n/a |
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| Ki | 9300.0±n/a nM |
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| Comments | extracted |
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| Citation |  Li, Z; Patil, GS; Golubski, ZE; Hori, H; Tehrani, K; Foreman, JE; Eveleth, DD; Bartus, RT; Powers, JC Peptide alpha-keto ester, alpha-keto amide, and alpha-keto acid inhibitors of calpains and other cysteine proteases. J Med Chem36:3472-80 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin B |
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| Name: | Cathepsin B |
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| Synonyms: | BCSB | CATB_BOVIN | CTSB | Cathepsin B precursor | Cathepsin B1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 36657.87 |
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| Organism: | Bos taurus (bovine) |
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| Description: | Bovine spleen CB was purchased from Sigma Co. (USA). |
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| Residue: | 335 |
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| Sequence: | MWRLLATLSCLLVLTSARSSLYFPPLSDELVNFVNKQNTTWKAGHNFYNVDLSYVKKLCG
AILGGPKLPQRDAFAADVVLPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDR
ICIHSNGRVNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCR
PYSIPPCEHHVNGSRPPCTGEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIM
AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSW
NTDWGDNGFFKILRGQDHCGIESEIVAGMPCTHQY
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| BDBM50042411 |
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| n/a |
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| Name | BDBM50042411 |
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| Synonyms: | CHEMBL331850 | [1-(1-Benzyl-2-oxo-2-phenethylcarbamoyl-ethylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C32H37N3O5 |
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| Mol. Mass. | 543.6533 |
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| SMILES | CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)NCCc1ccccc1 |
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| Structure | 
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