| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50043214 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_29299 (CHEMBL640360) |
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| Ki | 25.3±n/a nM |
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| Citation |  Peet, NP; Lentz, NL; Dudley, MW; Ogden, AM; McCarty, DR; Racke, MM Xanthines with C8 chiral substituents as potent and selective adenosine A1 antagonists. J Med Chem36:4015-20 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50043214 |
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| n/a |
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| Name | BDBM50043214 |
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| Synonyms: | 8-(1-Phenyl-ethyl)-1,3-dipropyl-3,9-dihydro-purine-2,6-dione | CHEMBL128804 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H24N4O2 |
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| Mol. Mass. | 340.4195 |
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| SMILES | CCCn1c2[nH]c(nc2c(=O)n(CCC)c1=O)[C@H](C)c1ccccc1 |
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| Structure | 
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