| Reaction Details |
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 | Report a problem with these data |
| Target | Glutathione S-transferase A1 |
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| Ligand | BDBM50043760 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_72446 (CHEMBL682616) |
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| Ki | 14700±n/a nM |
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| Citation |  Lyttle, MH; Hocker, MD; Hui, HC; Caldwell, CG; Aaron, DT; Engqvist-Goldstein, A; Flatgaard, JE; Bauer, KE Isozyme-specific glutathione-S-transferase inhibitors: design and synthesis. J Med Chem37:189-94 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutathione S-transferase A1 |
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| Name: | Glutathione S-transferase A1 |
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| Synonyms: | GST class-alpha member 1 | GST-epsilon | GSTA1 | GSTA1-1 | GSTA1_HUMAN | GTH1 | Glutathione S-transferase (GST) | HA subunit 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 25636.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Glutathione-S-Transferase (GST, N-terminally) |
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| Residue: | 222 |
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| Sequence: | MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
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| BDBM50043760 |
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| n/a |
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| Name | BDBM50043760 |
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| Synonyms: | 2-Amino-4-[1-[(carboxy-phenyl-methyl)-carbamoyl]-2-(4-chloro-benzylsulfanyl)-ethylcarbamoyl]-butyric acid | CHEMBL442360 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26ClN3O6S |
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| Mol. Mass. | 507.987 |
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| SMILES | NC(CCC(=O)NC(CSCc1ccc(Cl)cc1)C(=O)NC(C(O)=O)c1ccccc1)C(O)=O |
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| Structure | 
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