| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinoic acid receptor alpha |
|---|
| Ligand | BDBM50044098 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_195316 (CHEMBL799871) |
|---|
| IC50 | >1000±n/a nM |
|---|
| Citation |  Boehm, MF; McClurg, MR; Pathirana, C; Mangelsdorf, D; White, SK; Hebert, J; Winn, D; Goldman, ME; Heyman, RA Synthesis of high specific activity [3H]-9-cis-retinoic acid and its application for identifying retinoids with unusual binding properties. J Med Chem37:408-14 (1994) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinoic acid receptor alpha |
|---|
| Name: | Retinoic acid receptor alpha |
|---|
| Synonyms: | NR1B1 | Nuclear receptor subfamily 1 group B member 1 | RAR-alpha | RARA | RARA_HUMAN | Retinoic acid receptor alpha | Retinoic acid receptor alpha/Retinoid X receptor alpha | Retinoid X receptor gamma/retinoic acid receptor alpha | Retinoid receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 50778.87 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1466191 |
|---|
| Residue: | 462 |
|---|
| Sequence: | MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
|
|
|
|---|
| BDBM50044098 |
|---|
| n/a |
|---|
| Name | BDBM50044098 |
|---|
| Synonyms: | 4-[(E)-2-(3-Isopropyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-benzoic acid | CHEMBL424636 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H34O2 |
|---|
| Mol. Mass. | 390.5577 |
|---|
| SMILES | CC(C)c1cc2c(cc1\C(C)=C\c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
