Ki Summary

Reaction Details

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Target

B2 bradykinin receptor

Ligand

BDBM50045212

Substrate/Competitor

n/a

Meas. Tech.

ChEBML_40275

82±n/a nM

Citation

Chakravarty, S; Wilkins, D; Kyle, DJ Design of potent, cyclic peptide bradykinin receptor antagonists from conformationally constrained linear peptides. J Med Chem36:2569-71 (1993) [PubMed]

More Info.:

Get all data from this article, Assay Method

B2 bradykinin receptor

Name:

B2 bradykinin receptor

Synonyms:

Type:

n/a

Mol. Mass.:

42217.03

Organism:

Cavia porcellus

Description:

n/a

Residue:

372

Sequence:

MFNITSQVSALNATLAQGNSCLDAEWWSWLNTIQAPFLWVLFVLAVLENIFVLSVFFLHK
SSCTVAEIYLGNLAVADLILAFGLPFWAITIANNFDWLFGEVLCRMVNTMIQMNMYSSIC
FLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCALLLSSPMLVFRTMKDYRDEGH
NVTACLIIYPSLTWQVFTNVLLNLVGFLLPLSIITFCTVQIMQVLRNNEMQKFKEIQTER
RATVLVLAVLLLFVVCWLPFQIGTFLDTLRLLGFLPGCWEHVIDLITQISSYLAYSNSCL
NPLVYVIVGKRFRKKSREVYHGLCRSGGCVSEPAQSENSMGTLRTSISVDRQIHKLQDWA
RSSSEGTPPGLL

BDBM50045212

n/a

Name

BDBM50045212

Synonyms:

CHEMBL2370041 | D-Arg-Arg-Pro-Hyp-Gly-Phe-Ser-D-Tic-Oic-Arg

Type

Small organic molecule

Emp. Form.

C62H93N19O13

Mol. Mass.

1312.5213

SMILES

[#6]-[#6](-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H](-[#8])-[#6]-[#7]-1-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-1-[#6]-c2ccccc2-[#6]-[#6@@H]-1-[#6](=O)-[#7]-1-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](-[#8])=O

Structure