| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50045782 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_220942 |
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| Ki | 1±n/a nM |
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| Citation |  Mitch, CH; Leander, JD; Mendelsohn, LG; Shaw, WN; Wong, DT; Cantrell, BE; Johnson, BG; Reel, JK; Snoddy, JD; Takemori, AE 3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines: opioid antagonists with potent anorectant activity. J Med Chem36:2842-50 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42744.99 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | P41144 |
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| Residue: | 380 |
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| Sequence: | MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
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| BDBM50045782 |
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| n/a |
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| Name | BDBM50045782 |
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| Synonyms: | 3-[1-(2-Cyclopent-2-enyl-ethyl)-3,4-dimethyl-piperidin-4-yl]-phenol | CHEMBL317936 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H29NO |
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| Mol. Mass. | 299.4504 |
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| SMILES | C[C@H]1CN(CCC2CCC=C2)CC[C@@]1(C)c1cccc(O)c1 |c:9| |
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| Structure | 
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