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TargetMu-type opioid receptor
LigandBDBM50045784
Substrate/Competitorn/a
Meas. Tech.ChEMBL_221941 (CHEMBL881435)
Ki 0.890000±n/a nM
Citation Mitch, CHLeander, JDMendelsohn, LGShaw, WNWong, DTCantrell, BEJohnson, BGReel, JKSnoddy, JDTakemori, AE 3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines: opioid antagonists with potent anorectant activity. J Med Chem36:2842-50 (1993) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44503.11
Organism:Rattus norvegicus (rat)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50045784
n/a
NameBDBM50045784
Synonyms:(3R,4R)3-[3,4-Dimethyl-1-(5-methyl-hexyl)-piperidin-4-yl]-phenol | 3-[3,4-Dimethyl-1-(5-methyl-hexyl)-piperidin-4-yl]-phenol | CHEMBL98568
TypeSmall organic molecule
Emp. Form.C20H33NO
Mol. Mass.303.4821
SMILESCC(C)CCCCN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1
Structure
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