| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50045784 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_220942 (CHEMBL824008) |
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| Ki | 1.91±n/a nM |
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| Citation |  Mitch, CH; Leander, JD; Mendelsohn, LG; Shaw, WN; Wong, DT; Cantrell, BE; Johnson, BG; Reel, JK; Snoddy, JD; Takemori, AE 3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines: opioid antagonists with potent anorectant activity. J Med Chem36:2842-50 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42744.99 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | P41144 |
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| Residue: | 380 |
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| Sequence: | MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
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| BDBM50045784 |
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| n/a |
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| Name | BDBM50045784 |
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| Synonyms: | (3R,4R)3-[3,4-Dimethyl-1-(5-methyl-hexyl)-piperidin-4-yl]-phenol | 3-[3,4-Dimethyl-1-(5-methyl-hexyl)-piperidin-4-yl]-phenol | CHEMBL98568 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H33NO |
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| Mol. Mass. | 303.4821 |
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| SMILES | CC(C)CCCCN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1 |
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| Structure | 
|
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