Reaction Details | |||
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Target | Gastrin/cholecystokinin type B receptor | ||
Ligand | BDBM50045806 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_49880 | ||
Ki | 50±n/a nM | ||
Citation | Blommaert, AG; Weng, JH; Dorville, A; McCort, I; Ducos, B; Durieux, C; Roques, BP Cholecystokinin peptidomimetics as selective CCK-B antagonists: design, synthesis, and in vitro and in vivo biochemical properties. J Med Chem36:2868-77 (1993) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
Gastrin/cholecystokinin type B receptor | |||
Name: | Gastrin/cholecystokinin type B receptor | ||
Synonyms: | CCK-2 receptor | CCK-B receptor | CCK-BR | CCKBR | CCKRB | Cholecystokinin A | Cholecystokinin receptor | Cholecystokinin-2 Receptor | GASR_HUMAN | Gastrin/cholecystokinin type B receptor | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 48445.79 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Stable expression of human CCK-2 receptors in HEK 293 cells. | ||
Residue: | 447 | ||
Sequence: |
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BDBM50045806 | |||
n/a | |||
Name | BDBM50045806 | ||
Synonyms: | CHEMBL320399 | {[2-(Adamantan-2-yloxycarbonylamino)-3-(4-bromo-phenyl)-2-methyl-propionyl]-phenethyl-amino}-acetic acid | ||
Type | Small organic molecule | ||
Emp. Form. | C31H37BrN2O5 | ||
Mol. Mass. | 597.54 | ||
SMILES | CC(Cc1ccc(Br)cc1)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=O)N(CCc1ccccc1)CC(O)=O |wU:19.20,17.24,15.16,wD:21.23,TLB:13:14:16:19.23.18,THB:20:21:16:19.23.18,20:19:14.21.22:16,(17.3,-9.45,;15.98,-10.23,;14.64,-11,;14.66,-12.56,;15.99,-13.31,;16,-14.85,;14.67,-15.63,;14.67,-17.17,;13.33,-14.87,;13.31,-13.34,;14.47,-9.82,;13.12,-9.05,;12.04,-10.13,;12.74,-7.56,;11.25,-7.15,;9.5,-7.16,;8.43,-8.19,;7.15,-7.56,;6.6,-6.15,;7.72,-5.1,;9.35,-4.94,;9.92,-6.36,;8.77,-7.47,;8.94,-5.87,;17.31,-11,;17.3,-12.53,;18.85,-10.99,;19.63,-9.66,;21.17,-9.66,;21.94,-8.31,;23.48,-8.31,;24.25,-6.99,;23.48,-5.64,;21.92,-5.66,;21.16,-6.99,;19.63,-12.33,;21.17,-12.33,;21.94,-13.66,;21.94,-10.99,)| | ||
Structure |