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TargetD(1A) dopamine receptor
LigandBDBM50029413
Substrate/Competitorn/a
Meas. Tech.ChEBML_58181
IC50 9.5±n/a nM
Citation Palm, JBøgesø, KPLiljefors, T A structure-activity study of four dopamine D-1 and D-2 receptor antagonists, representing the phenylindan, -indene, and -indole structural classes of compounds. J Med Chem36:2878-85 (1993) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
D(1A) dopamine receptor
Name:D(1A) dopamine receptor
Synonyms:DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:Enzyme Catalytic Domain
Mol. Mass.:49429.75
Organism:RAT
Description:P18901
Residue:446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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  Blast E-value cutoff:
BDBM50029413
n/a
NameBDBM50029413
Synonyms:1-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-4-methyl-piperazine | CHEMBL318714
TypeSmall organic molecule
Emp. Form.C20H22ClFN2
Mol. Mass.344.853
SMILESCN1CCN(CC1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1
Structure
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