| Reaction Details |
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 | Report a problem with these data |
| Target | Amiloride-sensitive amine oxidase [copper-containing] |
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| Ligand | BDBM50046202 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_53893 |
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| IC50 | 7500±n/a nM |
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| Citation |  Stanek, J; Caravatti, G; Capraro, HG; Furet, P; Mett, H; Schneider, P; Regenass, U S-adenosylmethionine decarboxylase inhibitors: new aryl and heteroaryl analogues of methylglyoxal bis(guanylhydrazone). J Med Chem36:46-54 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Amiloride-sensitive amine oxidase [copper-containing] |
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| Name: | Amiloride-sensitive amine oxidase [copper-containing] |
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| Synonyms: | ABP | AOC1_RAT | Abp1 | Amiloride-binding protein | Aoc1 | DAO | Diamine oxidase | Histaminase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 85028.72 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_53893 |
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| Residue: | 746 |
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| Sequence: | MCLAFGWAAVILVLQTVDTASAVRTPYDKARVFADLSPQEIKAVHSFLMNREELGLQPSK
EPTLAKNSVFLIEMLLPKKKHVLKFLDEGRKGPNREARAVIFFGAQDYPNVTEFAVGPLP
RPYYIRALSPRPGHHLSWSSRPISTAEYDLLYHTLKRATMPLHQFFLDTTGFSFLGCDDR
CLTFTDVAPRGVASGQRRSWFIVQRYVEGYFLHPTGLEILLDHGSTDVQDWRVEQLWYNG
KFYNNPEELARKYAVGEVDTVVLEDPLPNGTEKPPLFSSYKPRGEFHTPVNVAGPHVVQP
SGPRYKLEGNTVLYGGWSFSYRLRSSSGLQIFNVLFGGERVAYEVSVQEAVALYGGHTPA
GMQTKYIDVGWGLGSVTHELAPGIDCPETATFLDAFHYYDSDGPVHYPHALCLFEMPTGV
PLRRHFNSNFKGGFNFYAGLKGYVLVLRTTSTVYNYDYIWDFIFYSNGVMEAKMHATGYV
HATFYTPEGLRHGTRLQTHLLGNIHTHLVHYRVDMDVAGTKNSFQTLTMKLENLTNPWSP
SHSLVQPTLEQTQYSQEHQAAFRFGQTLPKYLLFSSPQKNCWGHRRSYRLQIHSMAEQVL
PPGWQEERAVTWARYPLAVTKYRESERYSSSLYNQNDPWDPPVVFEEFLRNNENIEDEDL
VAWVTVGFLHIPHSEDVPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPQDKGLNR
VQRWIPEDRRCLVSPPFSYNGTYKPV
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| BDBM50046202 |
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| n/a |
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| Name | BDBM50046202 |
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| Synonyms: | 6-((E)-{[(E)-amino(hydroxyimino)methyl]hydrazono}methyl)pyridine-2-carboximidamide | CHEMBL342495 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H11N7O |
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| Mol. Mass. | 221.2192 |
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| SMILES | NC(NO)=NN=Cc1cccc(n1)C(N)=N |w:4.4,6.6| |
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| Structure | 
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