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TargetTrypsin-1
LigandBDBM50060000
Substrate/Competitorn/a
Meas. Tech.ChEMBL_213037
IC50 18±n/a nM
Citation Shuman RTRothenberger RBCampbell CSSmith GFGifford-Moore DSGesellchen PD Highly selective tripeptide thrombin inhibitors. J Med Chem 36:314-9 (1993) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Trypsin-1
Name:Trypsin-1
Synonyms:Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | Trypsin | Trypsin I
Type:Enzyme
Mol. Mass.:26557.80
Organism:Homo sapiens (Human)
Description:P07477
Residue:247
Sequence:
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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  Blast E-value cutoff:
BDBM50060000
n/a
NameBDBM50060000
Synonyms:(S)-1-((R)-2-Methylamino-2-phenyl-acetyl)-pyrrolidine-2-carboxylic acid ((S)-1-formyl-4-guanidino-butyl)-amide | CHEMBL105205
TypeSmall organic molecule
Emp. Form.C20H30N6O3
Mol. Mass.402.4906
SMILESCN[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C=O)c1ccccc1
Structure
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