| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
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| Ligand | BDBM50047068 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_207650 (CHEMBL811632) |
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| Ki | 6±n/a nM |
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| Citation |  Nicolaï, E; Goyard, J; Benchetrit, T; Teulon, JM; Caussade, F; Virone, A; Delchambre, C; Cloarec, A Synthesis and structure-activity relationships of novel benzimidazole and imidazo[4,5-b]pyridine acid derivatives as thromboxane A2 receptor antagonists. J Med Chem36:1175-87 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Thromboxane A2 receptor |
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| Name: | Thromboxane A2 receptor |
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| Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
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| Type: | Enyzme |
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| Mol. Mass.: | 37445.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21731 |
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| Residue: | 343 |
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| Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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| BDBM50047068 |
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| n/a |
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| Name | BDBM50047068 |
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| Synonyms: | 4-[5-Chloro-1-(4-methylsulfanyl-benzyl)-1H-benzoimidazol-2-yl]-3,3-dimethyl-butyric acid | CHEMBL18000 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23ClN2O2S |
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| Mol. Mass. | 402.938 |
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| SMILES | CSc1ccc(Cn2c(CC(C)(C)CC(O)=O)nc3cc(Cl)ccc23)cc1 |
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| Structure | 
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