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TargetType-1 angiotensin II receptor
LigandBDBM50047132
Substrate/Competitorn/a
Meas. Tech.ChEMBL_36780 (CHEMBL650301)
IC50 14±n/a nM
Citation Bradbury, RHAllott, CPDennis, MGirdwood, JAKenny, PWMajor, JSOldham, AARatcliffe, AHRivett, JERoberts, DA New nonpeptide angiotensin II receptor antagonists. 3. Synthesis, biological properties, and structure-activity relationships of 2-alkyl-4-(biphenylylmethoxy)pyridine derivatives. J Med Chem36:1245-54 (1993) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Type-1 angiotensin II receptor
Name:Type-1 angiotensin II receptor
Synonyms:AGTR1 | AGTR1_CAVPO | AT1 | Angiotensin II type-1 receptor
Type:PROTEIN
Mol. Mass.:41004.19
Organism:Cavia porcellus
Description:ChEMBL_36783
Residue:359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADICFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCVIIWLMAGLASLPAVIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFMFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIHDCKISDIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSTLSTKMSTLSYRPSDNVSSSAKKPVQCFEVE
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  Blast E-value cutoff:
BDBM50047132
n/a
NameBDBM50047132
Synonyms:2,6-Diethyl-3-iodo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethoxy]-pyridine | CHEMBL285560 | i2,6-Diethyl-3-iodo-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethoxy]-pyridine
TypeSmall organic molecule
Emp. Form.C23H22IN5O
Mol. Mass.511.3582
SMILESCCc1cc(OCc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c(I)c(CC)n1
Structure
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