| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 4A4 |
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| Ligand | BDBM50047304 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_52074 |
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| Ki | 1800±n/a nM |
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| Citation |  Burger, A; Clark, JE; Nishimoto, M; Muerhoff, AS; Masters, BS; Ortiz de Montellano, PR Mechanism-based inhibitors of prostaglandin omega-hydroxylase: (R)- and (S)-12-hydroxy-16-heptadecynoic acid and 2,2-dimethyl-12-hydroxy-16-heptadecynoic acid. J Med Chem36:1418-24 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 4A4 |
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| Name: | Cytochrome P450 4A4 |
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| Synonyms: | CP4A4_RABIT | CYP4A4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58951.27 |
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| Organism: | Oryctolagus cuniculus |
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| Description: | ChEMBL_52074 |
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| Residue: | 510 |
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| Sequence: | MSVSALSPTRLPGSLSGLLQVAALLGLLLLLLKAAQLYLHRQWLLRALQQFPCPPFHWLL
GHSREFQNDQELERIQKWVEKFPGACPWWLSGNKARLLVYDPDYLKVILGRSDPKAPRNY
KLMTPWIGYGLLLLDGQTWFQHRRMLTPAFHYDILKPYVGLMVDSVQIMLDRWEQLISQD
SSLEIFQHVSLMTLDTIMKCAFSYQGSVQLDRNSHSYIQAINDLNNLVFYRARNVFHQSD
FLYRLSPEGRLFHRACQLAHEHTDRVIQQRKAQLQQEGELEKVRRKRRLDFLDVLLFAKM
ENGSSLSDQDLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQHRCREEIQGLLGDGAS
ITWEHLDQMPYTTMCIKEALRLYPPVPSVTRQLSKPVTFPDGRSLPKGVILFLSIYGLHY
NPKVWQNPEVFDPFRFAPDSAYHSHAFLPFSGGARNCIGKQFAMRELKVAVALTLVRFEL
LPDPTRIPIPIARVVLKSKNGIHLRLRKLH
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| BDBM50047304 |
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| n/a |
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| Name | BDBM50047304 |
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| Synonyms: | 12-Hydroxy-heptadec-16-ynoic acid | CHEMBL33390 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H30O3 |
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| Mol. Mass. | 282.4183 |
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| SMILES | O[C@@H](CCCCCCCCCCC(O)=O)CCCC#C |
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| Structure | 
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