Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
Target5-hydroxytryptamine receptor 1D
LigandBDBM30707
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1628 (CHEMBL616514)
Ki 20±n/a nM
Citation Glennon, RA; Hong, SS; Bondarev, M; Law, H; Dukat, M; Rakhi, S; Power, P; Fan, E; Kinneau, D; Kamboj, R; Teitler, M; Herrick-Davis, K; Smith, C Binding of O-alkyl derivatives of serotonin at human 5-HT1D beta receptors. J Med Chem39:314-22 (1996) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 1D
Name:5-hydroxytryptamine receptor 1D
Synonyms:5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor | Serotonin Receptor 1D
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:41920.63
Organism:Homo sapiens (Human)
Description:Receptor binding assays were performed using human clone stably expressed in CHO cells.
Residue:377
Sequence:
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM30707
n/a
NameBDBM30707
Synonyms:2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamine | 2-(5-methoxy-1H-indol-3-yl)-N,N-dimethylethanamine | 2-(5-methoxy-1H-indol-3-yl)ethyl-dimethyl-amine | 3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7257 | MLS000069438 | Methoxydimethyltryptamines | SMR000059066 | WO2023019367, Compound 5-MeO-DMT | cid_1832
TypeSmall organic molecule
Emp. Form.C13H18N2O
Mol. Mass.218.2948
SMILESCOc1ccc2[nH]cc(CCN(C)C)c2c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: